Explain what is meant by metastasis.
Metastasis is the property of malignant tumors where cells sloughed from the tumor reach distant sites through blood. Wherever these cells get lodged in the body, they start a new tumor there.
This property is considered the most feared property of malignant tumors because it enables cancer cells to spread to different parts of the body from the original location. The cancerous cells grow rapidly, invade and damage surrounding normal tissues, and compete with normal cells for vital nutrients.
Explanation
The textbook defines metastasis specifically in the context of malignant tumors. The key points are: (1) cells detach from the tumor, (2) travel through blood to distant sites, (3) get lodged at new locations, and (4) start new tumors there. This distinguishes malignant tumors from benign tumors, which remain confined to their original location. The 2-mark answer covers the definition and significance of metastasis.
Solution Steps
Step 1: Define metastasis as the property of malignant tumors to spread to distant sites
Step 2: Explain the mechanism - cells slough off, travel via blood, lodge elsewhere, and form new tumors
Step 3: Mention why it is medically significant (most feared property)