Name the hormones involved in regulation of spermatogenesis.
The hormones involved in regulation of spermatogenesis are:
Gonadotropin Releasing Hormone (GnRH) is a hypothalamic hormone whose significant increase in secretion at puberty initiates spermatogenesis. GnRH acts at the anterior pituitary gland and stimulates secretion of two gonadotropins – Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH).
LH acts at the Leydig cells and stimulates synthesis and secretion of androgens. Androgens, in turn, stimulate the process of spermatogenesis. FSH acts on the Sertoli cells and stimulates secretion of some factors which help in the process of spermiogenesis.
Explanation
This 2-mark question requires students to identify all hormones in the regulatory cascade. The textbook clearly outlines the pathway: GnRH (hypothalamus) → LH and FSH (anterior pituitary) → Androgens (Leydig cells) → Spermatogenesis. FSH acts independently on Sertoli cells to support spermiogenesis. Students should mention all four hormones for full marks.
Solution Steps
Step 1: Identify the initiating hormone - GnRH from hypothalamus
Step 2: Identify the pituitary gonadotropins stimulated by GnRH - LH and FSH
Step 3: Identify the testicular hormones - Androgens (stimulated by LH)
Step 4: Mention FSH's role in stimulating Sertoli cells for spermiogenesis