Question 1 of 10intermediate🔧 ApplyLong Answer3 marks

Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (use the internet).

Correct Answer

Note: The provided textbook context does not contain the list of 10 recombinant proteins or their therapeutic uses. The context only defines a recombinant protein as a protein encoding gene expressed in a heterologous host, and describes the general process of large-scale production using bioreactors.

However, based on the question's instruction to "use the internet," here is the standard answer expected:

10 Recombinant Proteins Used in Medical Practice:

  1. Insulin – Used for diabetes mellitus treatment
  2. Human Growth Hormone (hGH) – Used for growth deficiency disorders
  3. Interferon-alpha – Used for treating hepatitis C and certain cancers
  4. Interferon-beta – Used for multiple sclerosis treatment
  5. Erythropoietin (EPO) – Used for anemia treatment
  6. Tissue Plasminogen Activator (tPA) – Used for dissolving blood clots in heart attacks
  7. Factor VIII – Used for hemophilia A treatment
  8. Granulocyte Colony Stimulating Factor (G-CSF) – Used for neutropenia treatment
  9. Monoclonal Antibodies – Used for various cancers and autoimmune diseases
  10. Hepatitis B Surface Antigen – Used as vaccine against Hepatitis B

These recombinant proteins are produced by expressing the human gene in host organisms like bacteria or yeast, then purified for therapeutic use.

Exercise: EXERCISES | Q: 1 | (Page 15)
For More Understanding

Explanation

The textbook context (Chapter 9: Biotechnology Principles and Processes) only provides the definition and production process of recombinant proteins but does not list specific examples. The question itself instructs students to research using the internet, indicating this information is not contained within the chapter text. Students are expected to research independently to find these therapeutic applications.

Solution Steps

  1. Step 1: Identify that the context defines recombinant proteins as proteins expressed in heterologous hosts

  2. Step 2: Note that specific examples and therapeutic uses are not in the provided text

  3. Step 3: Recognize the question requires internet research as stated in the textbook

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