Question 21 of 21intermediate🔍 AnalyzeMCQ1 mark

Assertion: Cell lines derived from the primary culture of normal cells are finite cell line. Reason: Some cells of the finite cell line undergoes transformation and retain the ability to divide indefinitely.

Exercise: EXERCISES | Q: 21 | (Page 24)
For More Understanding

Explanation

The assertion is TRUE as the context explicitly states: 'Cell lines derived from primary cultures of normal cells are finite cell lines.' However, the reason is FALSE. The context states that 'Some cells of the finite cell line undergo transformation and resume the ability to divide indefinitely, and become a continuous cell line.' The reason incorrectly uses the word 'retain' instead of 'resume' and fails to mention that these transformed cells become a continuous cell line, not a finite cell line. Additionally, the reason does not explain why cell lines derived from primary cultures of normal cells are finite; it describes a different phenomenon altogether - the transformation of finite cell lines into continuous cell lines.

Solution Steps

  1. Step 1: Verify the assertion from context - 'Cell lines derived from primary cultures of normal cells are finite cell lines' is stated verbatim, so assertion is TRUE.

  2. Step 2: Verify the reason from context - Context states cells 'resume' (not 'retain') the ability to divide indefinitely and 'become a continuous cell line'. The reason is FALSE.

  3. Step 3: Check if reason explains assertion - The reason describes transformation into continuous cell lines, which does not explain why primary culture-derived lines are finite.

  4. Step 4: Select option (C) - Assertion is true but reason is false.